T3 Liothyronine Sodium + 5a-Hydroxy Laxogenin + SR-9011 + GW-0742 + Yohimbine Transdermal – Product Information
T3 Liothyronine Sodium + 5a-Hydroxy Laxogenin + SR-9011 + GW-0742 + Yohimbine Transdermal is a research compound designed to explore the potential effects of its unique combination of T3 Liothyronine Sodium, 5a-Hydroxy Laxogenin, SR-9011, GW-0742, and Yohimbine. This formulation has a collective impact on various aspects of lipid metabolism and energy regulation in preclinical models.
The Ultimate Transdermal is strictly intended for research purposes.
- The Transdermal consists of T3 Liothyronine Sodium, 5a-Hydroxy Laxogenin, SR-9011, GW-0742, and Yohimbine.
- The Transdermal is offered as 50mcg T3 Liothyronine Sodium, 7.5mg 5a-Hydroxy Laxogenin, 5mg SR9011, 5mg GW0742, and 2.5mg Yohimbine, totaling 20mg per ml for 60ml or 1200mg in total.
T3 Liothyronine Sodium
Thyroid hormones, specifically T3 Liothyronine Sodium, have garnered interest in research due to their potential interactions with fat mass. A recent study conducted on rats explored the effects of T3 supplementation and found that it did not abolish the increased expression of thyroid hormone receptor beta, which occurs during caloric restriction. Additionally, T3 supplementation led to increased leptin gene expression.
The data suggest that T3 may not significantly elevate metabolic rate but rather mitigate the decline typically observed during prolonged caloric restriction in research models.
| T3 Liothyronine Sodium Liquid | |
| CAS Number | 6893-02-3 |
| Molar Mass | 650,9735 g/mol |
| Chemical Formula | C15H12I3NO4 |
| IUPAC Name | sodium;(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
5a-Hydroxy Laxogenin |
5a-Hydroxy Laxogenin
Laxogenin, also known as 5 alpha hydroxy laxogenin or 5a hydroxy laxogenin, is a compound derived from plants and belongs to a group of compounds called brassinosteroids. While the exact mechanism of its effects is not yet fully understood, as a brassinosteroid, preliminary studies suggest its potential impact on increasing protein synthesis and reducing protein breakdown.
It is investigated for potential effects on protein synthesis and cortisol modulation in preclinical studies. Despite ongoing research, further investigation is needed to fully elucidate the mechanisms and potential benefits of laxogenin. It is important to note that this information is strictly related to research purposes.
| 5a-Hydroxy Laxogenin | |
| CAS Number | 56786-63-1 |
| Molar Mass | 446.6 g/mol |
| Chemical Formula | C27H42O |
| IUPAC Name | (1S,2S,4S,5’R,6R,7S,8R,9S,12S,13R,16S,18R)-16,18-dihydroxy-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2′-oxane]-19-one |
SR-9011
A recent study conducted on diet-induced obese mice investigated the effects of SR-9009 and SR-9011, administered twice daily for 30 days. The findings revealed a significant reduction in fat mass and notable improvements in dyslipidemia and hyperglycemia. Activation of REV-ERB, induced by these compounds, was observed to enhance the circadian rhythm in mice, impacting various aspects such as behavior, sleep cycles, and functions associated with increased energy production. These results offer valuable insights into the potential of SR9009 and SR-9011 in addressing obesity-related issues and optimizing metabolic function. It is important to note that this study was conducted for research purposes only.
| SR-9011 | |
| CAS Number | 1379686-29-9 |
| Molar Mass | 479.04 g/mol |
| Chemical Formula | C23H31ClN4O3S |
| IUPAC Name | 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
GW-0742
GW-0742 is a PPARβ/δ agonist, which is being dubbed as a ‘Super Cardarine’. Studies have shown that GW0742 has the ability to improve glucose homeostasis and increase insulin sensitivity in diabetic rats. In diabetic rats fed a high fructose diet, a group given GW0742 showed lower blood sugar compared to the control group.
Due to GW0742 being a PPAR agonist, it showed the potential to be studied in research models for its effects on energy metabolism and fat utilization. This has been studied in research models for potential effects on energy metabolism and oxidative capacity in muscle tissue.
| GW0742 | |
| CAS Number | 317318-84-6 |
| Molar Mass | 471.48 g/mol |
| Chemical Formula | C21H17F4NO3S2 |
| IUPAC Name | 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid |
Yohimbine
Yohimbine is a compound derived from the bark of the Yohimbe tree (Pausinystalia yohimbe) and is of interest in research fields. It is classified as an alpha-2 adrenergic receptor antagonist, which means it blocks the action of these receptors. Yohimbine has been studied for its potential effects on various physiological processes. Preclinical studies show Yohimbine’s cardiovascular and adrenergic responses, and its potential to promote lipolytic activity in preclinical models.
| Yohimbine | |
| CAS Number | 146-48-5 |
| Molar Mass | 354.450 g/mol |
| Chemical Formula | C21H26N2O3 |
| IUPAC Name | 17α-hydroxy-yohimban-16α-carboxylic acid methyl ester
Disclaimer |
Disclaimer
This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC), following the guidelines of the Animal Welfare Act (AWA).
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ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.
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External Research Resources
- PubChem – Scientific compound database for molecular validation and structure review.
- NCBI – Peer-reviewed biomedical literature and compound research studies.
- ClinicalTrials.gov – Clinical study database for metabolic and investigational compounds.
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